The FDA is strengthening an earlier warning about the cardiovascular safety of NSAIDs, both prescription and non-prescription. The FDA is requiring updates to the labels of all prescription NSAIDs to reflect recent information on risk of heart attack and stroke. Over-the-counter non-aspirin NSAIDs already contain some safety information, but the labels on these drugs will also require an update, according to the agency’s announcement. MedPage Today reports that, “this latest warning follows at least a decade of concern about the safety of NSAIDs. In 2005, the FDA issued a warning about NSAIDs and asked Pfizer to withdraw its drug valdecoxib (Bextra) from the market after concerns about an increased risk of cardiovascular events and serious skin reactions.” The American Heart Association also issued a warning about the use of NSAIDs in 2013.
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